p75NTR Mediates Ephrin-A Reverse Signaling Required for Axon Repulsion and Mapping
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منابع مشابه
p75NTR Mediates Ephrin-A Reverse Signaling Required for Axon Repulsion and Mapping
Reverse signaling by ephrin-As upon binding EphAs controls axon guidance and mapping. Ephrin-As are GPI-anchored to the membrane, requiring that they complex with transmembrane proteins that transduce their signals. We show that the p75 neurotrophin receptor (NTR) serves this role in retinal axons. p75(NTR) and ephrin-A colocalize within caveolae along retinal axons and form a complex required ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2008
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2008.07.032